orcid ID 0000-0002-0169-4441
Current Position: Valentina Sepe, PhD, is researcher of Organic Chemistry since 2010 at the University of Naples “Federico II”
Research activity and interest: Dr. Sepe’s research (LyRiSyM group) is involved in the design and synthesis of new ligands as selective and/or dual modulators of bile acid receptors, FXR and GPBAR1. The research activity is focused towards the design and the synthesis of new leads as promising therapeutic strategy in metabolic syndrome. The research line focused on the synthesis of bile acid derivatives is part of a research agreement with BAR Pharmaceuticals. Recently, the research has also shifted towards the synthesis of steroidal and aromatic compounds with the aim of obtaining multi-target derivatives, such as for example dual agonists of GPBAR1 and CysLT1 receptors.
This well consolidated works led to 24 joint papers (2011-2020) on peer-review journals.